abstract：BACKGROUND AND OBJECTIVES:Although health risks associated to excessive body fat increase with small increases in body weight, measurement of body fat is usually grouped in very few categories. The aim of our study was to assess whether the risk for a combined end-point including the incidence of either hypertension an...

journal_title：Medicina clinica

authors： Toledo E,Beunza JJ,Núñez-Córdoba JM,Bes-Rastrollo M,Basterra-Gortari FJ,Martínez-González MA

更新日期：2009-05-09 00:00:00

abstract：BACKGROUND AND OBJECTIVE:We aimed to evaluate the prognostic impact of the degree and time-point of arterial recanalization during the first 24h after tPA administration in patients with acute middle cerebral artery (MCA) occlusions. PATIENTS AND METHOD:We prospectively studied consecutive ischemic stroke patients tre...

journal_title：Medicina clinica

authors： Dorado L,Arenillas JF,Millán M,Pérez De La Ossa N,Guerrero C,Dávalos A

更新日期：2009-05-02 00:00:00

abstract：:In recent years the interest in understanding the clinical significance and the pathogenic mechanisms involved in vascular calcification has rapidly increased. There are three reasons that explain this increasing interest in vascular calcification by nephrologists: a) cardiovascular disease is the leading cause of dea...

journal_title：Medicina clinica

authors： Rodríguez Portillo JM

更新日期：2009-05-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:The REACH Registry is the largest worldwide designed to obtain information on cardiovascular risk factor control and preventive treatment in a population who have, or are at risk of having, symptoms of atherothrombosis. The objective of this study is to show the results of cardiovascular events...

journal_title：Medicina clinica

authors： Suárez C,Castillo J,Esmatjes E,Sala J,Cairols M,Montoto C,Barberá G,en representación de los investigadores del registro REACH España.

更新日期：2009-04-18 00:00:00

abstract：BACKGROUND AND OBJECTIVE:The objective of this study is to describe the incidence of hepatic dysfunction (HD) in our hospital and evaluate the possible risk factors associated with HD development as an improvement of the caring process received by patients treated with parenteral nutrition (PN). PATIENTS AND METHOD:A ...

journal_title：Medicina clinica

authors： Servia L,Schoenenberger JA,Trujillano J,Badia M,Rodríguez-Pozo A

更新日期：2009-02-07 00:00:00

abstract：BACKGROUND AND OBJECTIVE:The effects of rosiglitazone on the lipid profile are controversial, with related increases in the concentration of total and LDL cholesterol. Our objective is to evaluate the evolution of the concentration and size of LDL particles in a group of patients with type 2 diabetes mellitus taking ro...

journal_title：Medicina clinica

authors： Albaladejo Otón MD,Calle Luna JG,Granero Fernández E,Hernández Martínez AM,Parra Pallarés S,Martínez Hernández P

更新日期：2009-01-31 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Thalassemias are the most common single-gene disorders in the world population and the most important health problem in several countries. The best program of prevention of new births is prenatal diagnosis. Here we gather the experience from 1996 of the Spanish Group of Erythropathology related...

journal_title：Medicina clinica

authors： Ropero P,González FA,Hernández A,Sánchez H,Cela E,Villegas A

更新日期：2009-01-24 00:00:00

abstract：OBJECTIVE:Patient perception of clinical safety has been scantly studied. This study describes the frequency of clinical errors from a patient point of view, their perception of safety and its relationship with the information received. MATERIAL AND METHODS:Descriptive study based on a postal survey to 336 surgical pa...

journal_title：Medicina clinica

authors： Mira JJ,Aranaz JM,Vitaller J,Ziadi M,Lorenzo S,Rebasa P,Aibar-Remón C

更新日期：2008-12-01 00:00:00

abstract：BACKGROUND:For biomedical research findings to contribute toward health gains they must reach clinicians. Academic journals have historically been considered important information sources. Birken and Parkin found seven journals to most consistently contain the best pediatric evidence and, of these seven, four were gene...

journal_title：Medicina clinica

authors： Jones TH,Hanney S,Buxton MJ

更新日期：2008-12-01 00:00:00

abstract：:Through the Law 2/2004 on improving neighbourhoods, urban areas and towns requiring special attention, the Government of Catalonia set up a fund for financing projects prepared by town/city councils for the integral improvement of neighbourhoods. The Ministry of Health signed on to the strategy with The Neighbourhood ...

journal_title：Medicina clinica

authors： Sierra I,Cabezas C,Brugulat P,Mompart A

更新日期：2008-12-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:This study was aimed to verify whether it is possible to detect at hospital admission, by means of INTERMED, pneumonology patients at risk of "complexity" and of specialized psychosocial intervention. PATIENTS AND METHOD:With the Spanish version of INTERMED (for detection of risk for complexit...

journal_title：Medicina clinica

authors： Lobo E,de Jonge P,Huyse FJ,Rabanaque MJ,Suárez J,Lobo A

更新日期：2008-11-29 00:00:00

abstract：BACKGROUND AND OBJECTIVE:To know the frequency of nosocomial infection (NI) in surgical hip fracture patients and to analyze the risk factors that favor the NI development, especially its relationship with allogeneic blood transfusion (ABT) and intravenous iron administration. PATIENTS AND METHOD:Unicenter prospective...

journal_title：Medicina clinica

authors： Izuel Rami M,García Erce JA,Gómez-Barrera M,Cuenca Espiérrez J,Abad Sazatornil R,Rabanaque Hernández MJ

更新日期：2008-11-15 00:00:00

abstract：BACKGROUND AND OBJECTIVE:To determine whether in the Mexican population the spouses of patients with type 2 diabetes mellitus (DM2) have an increased risk of any degree of glucose intolerance compared with spouses of subjects without diabetes. SUBJECTS AND METHOD:An analytical cross-sectional study was made in the Fam...

journal_title：Medicina clinica

authors： Trejo-Arteaga JM,López-Carmona JM,Rodríguez-Moctezuma JR,Peralta-Pedrero ML,Escudero-Montero R,Gutiérrez Escolano MF

更新日期：2008-11-08 00:00:00

abstract：:Currently, pharmacological thromboprophylaxis is frequently required in patients undergoing surgery, due to the high risk of deep venous thrombosis in the perioperative period. The administration of these anticoagulant agents (in Spain, usually low molecular weight heparins or fondaparinux, and in future, probably als...

journal_title：Medicina clinica

authors： Llau JV,Sapena ML,López Forte C,Ferrandis R

更新日期：2008-11-01 00:00:00

abstract：:Tumor necrosis factor (TNF) alpha plays a central role in both the inflammatory response and that of the immune system. Thus, its blockade with the so-called anti-TNF agents (infliximab, etanercept and adalimumab) represents an important tool for the management of a variety of disorders, such as rheumatoid arthritis, ...

journal_title：Medicina clinica

authors： Sánchez Cano D,Callejas Rubio JL,Ortego Centeno N

更新日期：2008-10-11 00:00:00

abstract：BACKGROUND AND OBJECTIVE:The aim of the study was to assess the effect of adding spironolactone to hypertensive resistant (HTR) patients and characterize those who respond effectively. PATIENTS AND METHOD:Observational retrospective study on outpatients with HTR (being treated with at least 3 drugs at full doses, one ...

journal_title：Medicina clinica

authors： Rodilla E,Costa JA,Pérez-Lahiguera F,González C,Pascual JM

更新日期：2008-10-04 00:00:00

abstract：OBJECTIVE:To describe the secular trend of cancer incidence in Catalonia and to compare it with that observed in European regions. MATERIAL AND METHOD:Using data from the Tarragona and Gerona cancer registries, the number of cases, adjusted rates, and the annual percentages of change in cancer incidence in Catalonia f...

journal_title：Medicina clinica

authors： Borràs J,Ameijide A,Vilardell L,Valls J,Marcos-Gragera R,Izquierdo A

更新日期：2008-10-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Although constipation affects quality of life, questionnaires hardly exist for its evaluation. We aimed to develop and validate a questionnaire able to measure the quality of life in patients with constipation. PATIENTS AND METHOD:A Spanish multicenter study was performed in 2 stages: a) quest...

journal_title：Medicina clinica

authors： Perona M,Mearin F,Guilera M,Mínguez M,Ortiz V,Montoro M,Serra J,Casanova C,Rey E,Alarcón O,Bujanda L,Lima A,Andreu M,Castro M,López A,Carrillo R,Sempere L,Badia X,Study group on functional gastrointestinal disorders f

更新日期：2008-09-27 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Many studies have been performed on the ability of bone turnover markers (BTM) for the prediction of bone loss and to assess the correlation of BTM with bone mineral density (BMD). However, the results from these studies have been mixed. The aim of this study was to assess the usefulness of BTM...

journal_title：Medicina clinica

authors： Navarro Casado L,Blázquez Cabrera JA,Del Pino Montes J,Almar Marqués E,Cháfer Rudilla M,Mateos Rodríguez F

更新日期：2008-09-20 00:00:00

abstract：BACKGROUND AND OBJECTIVE:We intended to know the degree of agreement between the quality of life's perception of patients with home nutritional support and that of their main caregiver in the different dimensions. We also aimed to establish the predictive ability of the health-related quality of life (HRQL) punctuation...

journal_title：Medicina clinica

authors： Wanden-Berghe C,Nolasco A,Planas M,Sanz-Valero J,Rodríguez T,Cuerda C,Guardiola R,Castelló-Botia I,Grupo NADYA-SENPE.

更新日期：2008-09-13 00:00:00

abstract：:Pharmacogenetics studies the relationship between genetic polymorphisms and individual responses to drugs. In recent years, there has been a great progress in our knowledge of the effects of drug-metabolizing enzymes and molecular target genetic polymorfisms on cancer chemotherapy. Pharmacogenetics focuses on the pred...

journal_title：Medicina clinica

authors： Morán González D,Jiménez Cabrera S,Domínguez-Gil Hurlé A

更新日期：2008-07-05 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Dengue is the most common imported arbovirus infection in Europe. International travel and an increasing incidence of dengue fever in tropical areas have defined the disease as an emerging infection in returning travellers. We describe the clinical and microbiological features of imported dengu...

journal_title：Medicina clinica

authors： Muñoz J,Puente S,López-Vélez R,Domingo C,Ruiz J,Ramírez G,Navarro M,de Orye F,Sanz S,Rivas P,Turrientes MC,Tenorio A,Gascon J

更新日期：2008-06-07 00:00:00

abstract：BACKGROUND AND OBJECTIVE:There is contradictory evidence as to whether the pleiotropic effects of statins improve morbidity/mortality rates in coronary artery bypass grafting with extracorporeal circulation, as they reduce the protein plasma levels in the acute phase. PATIENTS AND METHOD:This randomized prospective st...

journal_title：Medicina clinica

authors： Tamayo E,Alonso O,Alvarez FJ,Castrodeza J,Flórez S,di Stefano S

更新日期：2008-05-31 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Alcohol and drug dependent patients present a higher psychiatric comorbidity, which increases according to the number of drugs. Moreover, there are complications from the treatment and the prognosis is aggravated. We aimed to observe the differences regarding personality disorders (PD) and cogn...

journal_title：Medicina clinica

authors： Monràs M,Mondón S,Jou J

更新日期：2008-05-17 00:00:00

abstract：:Difficulties derived from the big complexity of the human genome (because of the great amount of genes) and difficulties at the time of performing a correct molecular diagnosis have led to the utilization of advanced technologies such as DNA arrays. By this technique, it is possible to analyze in a single experiment g...

journal_title：Medicina clinica

authors： Sáenz A,López de Munain A

更新日期：2008-04-12 00:00:00

abstract：BACKGROUND AND OBJECTIVE:The aim of this study was to describe the evolution of serologically confirmed cases of mumps in the Madrid Community from 2000 to 2006. PATIENTS AND METHOD:Cases with data about age, sex and with samples obtained < or = 30 days after the onset of symptoms were included. IgM determination was ...

journal_title：Medicina clinica

authors： Sanz JC,de Ory F,Fernández M,Herranz N,Méndez N,Ramírez R

更新日期：2008-03-08 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Rheumatoid arthritis (RA) is characterized by high cardiovascular (CV) mortality, which seems related to systemic inflammation. Our aim was to quantify carotid atherosclerosis in RA and its relationship with the disease. PATIENTS AND METHOD:73 RA patients and the same number of sex and age mat...

journal_title：Medicina clinica

authors： García Díaz Jde D,López de Guzmán A,Díez-Pérez de la Vacas MI,Cuende Quintana E,Sánchez Atrio A

更新日期：2008-02-23 00:00:00

abstract：BACKGROUND AND OBJECTIVE:The effectiveness of the treatment of latent tuberculosis infection depends on its efficacy, the adherence to treatment and patient's risk of tuberculosis. The objective of this study was to evaluate the adherence to treatment with daily isoniazid for 9 months, its effectiviness and equivalent ...

journal_title：Medicina clinica

authors： Pina-Gutiérrez JM,Ferrer-Traid A,Arias C,Sala-Farré MR,López-Sanmartín JL

更新日期：2008-02-16 00:00:00

abstract：BACKGROUND AND OBJECTIVE:AIDS-related mortality has been classically associated with lowest socioeconomic groups. In Spain, the highly active antiretroviral therapy (HAART) is delivered without cost; therefore this treatment it should have reduced the great social inequalities in AIDS-mortality seen before the HAART er...

journal_title：Medicina clinica

authors： Sánchez E,Regidor E,de la Fuente L,Luquero FJ,de Mateo S

更新日期：2008-02-09 00:00:00

abstract：BACKGROUND AND AIMS:It has been recently shown that psychiatric disorders are associated with obesity. However this association has not been studied in overweight/obese patients at a hospital setting in our country. PATIENTS AND METHODS:We have studied 333 consecutive patients who were referred to our hospital outpati...

journal_title：Medicina clinica

authors： Vázquez C,Alcaraz F,Balsa JA,Zamarrón I,Arrieta F,Botella Carretero JI

更新日期：2008-01-26 00:00:00

abstract：BACKGROUND AND OBJECTIVE:The myocardial infarction (MI) with ST elevation and angiographically normal coronary arteries isn't frequent. The aim of this study is to describe clinical characteristic and mid-term follow-up of those patients. PATIENTS AND METHOD:Between January 1997 and December 2004 we identified 75 pati...

journal_title：Medicina clinica

authors： Ferrer Gracia MC,Hernández-Antolín RA,Pérez-Vizcayno MJ,Conde Vela C,Alfonso Manterola F,Macaya Miguel C

更新日期：2007-11-17 00:00:00

abstract：BACKGROUND AND OBJECTIVE:The impact and burden of disease of the rare diseases (RD) is not known, also the type of disability that entail. The objective of the work is to analyze the socio-sanitary impact of the RD in Spain. PATIENTS AND METHOD:This is a nationwide study. The dimensions used were mobility, personal ca...

journal_title：Medicina clinica

authors： Avellaneda Fernández A,Layola M,Izquierdo Martínez M,Guilera M,Badia Llach X,Ramón JR

更新日期：2007-11-10 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Since at present several diagnostic criteria of the metabolic syndrome (MS) exist, the objective of the study is to verify the utility of the criteria of the International Diabetes Federation (IDF) to diagnose the MS, their agreement with other previous definitions and the insulin resistance (I...

journal_title：Medicina clinica

authors： Martínez Candela J,Franch Nadal J,Romero Ortiz J,Cánovas Domínguez C,Gallardo Martín A,López Yepes ML

更新日期：2007-11-03 00:00:00

abstract：BACKGROUND AND OBJECTIVE:To analyze the serum levels of immunoglobulin G (IgG) subclasses in a broad range of elderly patients with bronchiectasis. PATIENTS AND METHOD:Data were collected from all patients who had a high-resolution chest computerized axial tomography diagnosis of bronchiectasis in our center. We gathe...

journal_title：Medicina clinica

authors： Martínez-García MA,Román-Sánchez P,Perpiñá-Tordera M,Soler-Cataluña JJ,Saura-Vinuesa A,Yago M,Pastor MJ

更新日期：2007-10-20 00:00:00

abstract：BACKGROUND AND OBJECTIVE:There are few epidemiological studies on massive transfusion (MT), although they may be important to evaluate possible strategies to reduce the number of transfused units, as well as transfusion side-effects. We, therefore, retrospectively assessed the incidence of MT at our institution (a 700-...

journal_title：Medicina clinica

authors： Campos A,Muñoz M,García-Erce JA,Ramírez G

更新日期：2007-09-22 00:00:00

abstract：BACKGROUND AND OBJECTIVE:To ascertain if a bilaterally lung transplanted patient can climb a mountain higher than 4,000 metres and to compare the evolution of his physiological parameters during the ascent with those of healthy mountaineers. SUBJECTS AND METHOD:Heart rate, blood pressure, arterial oxygen saturation (S...

journal_title：Medicina clinica

authors： Botella de Maglia J,Fuster Escrivà A

更新日期：2007-09-15 00:00:00

abstract：BACKGROUND AND OBJECTIVE:The influence of homocysteine metabolism on the prognosis of acute coronary syndrome without ST elevation is controversial. PATIENTS AND METHOD:Prospective study of 109 patients admitted because of acute coronary syndrome without ST elevation. Basal plasmatic levels of homocysteine and folates...

journal_title：Medicina clinica

authors： García-Pinilla JM,Espinosa-Caliani S,Gómez-Doblas JJ,Jiménez-Navarro MF,Cabrera-Bueno F,Muñoz Morán E,Ruiz-Galdón M,Reyes-Engel A,de Teresa Galván E

更新日期：2007-09-08 00:00:00

abstract：:Systemic autoinflammatory diseases are an heterogeneous group of systemic disorders clinically characterized by recurrent or persistent inflammatory episodes, which occur in the absence of infectious, neoplastic or autoimmune etiology. During the past years, genetic defects affecting different proteins involved in the...

journal_title：Medicina clinica

authors： Aróstegui JI,Yagüe J

更新日期：2007-07-14 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Almost 50% of gastrointestinal endoscopies performed in our Unit correspond to patients coming from primary care. Since resources are finite, adherence to appropriate indications for these procedures is essential. We prospectively assessed the appropriateness of gastrointestinal endoscopies ref...

journal_title：Medicina clinica

authors： Fernández-Esparrach G,Gimeno-García AZ,Llach J,Pellisé M,Ginès A,Balaguer F,Mata A,Castells A,Bordas JM

更新日期：2007-07-07 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Multiple chemical sensitivity (MCS) is characterized by a loss of tolerance to various environmental chemicals. The objective of this study was to describe patients with MCS seen in our hospital. PATIENTS AND METHOD:Patients consecutively seen by the Toxicology and Chronic Fatigue Units who pr...

journal_title：Medicina clinica

authors： Nogué S,Fernández-Solá J,Rovira E,Montori E,Fernández-Huerta JM,Munné P

更新日期：2007-06-16 00:00:00